If you have a Mac, get Fluid. When you run it, type in your Sproutit domain and name the app “Mailroom”. Fluid will create a native Mac application that you can launch just like Apple Mail, Safari or any other app, but this application will run Mailroom.

Apps like Mailroom work really well in this kind of environment. They honestly feel more at home this way than they do in a browser, IMO. I just tried this with the new version of Mailroom 3 we are working on and its even better.